产品详情
产品名称DNASE1L3 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen affinity purification.
应用WB
种属反应性Human
特异性The antibody detects endogenous levels of total DNASE1L3 protein.
免疫原类型Recombinant Protein
免疫原描述Fusion protein corresponding to a region derived from internal residues of human deoxyribonuclease I-like 3
基因/蛋白名称DNASE1L3
标记Unconjugated
别名LSD; DHP2; SLEB16; DNAS1L3
数据库入口号Swiss-Prot#: Q13609
NCBI Gene ID: 1776
Gene Accssion: BC015831
Uniprot
Q13609
实际分子量36kd
浓度0.9mg/ml
配方Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
保存Store at -20˚C
应用详情
Western blotting: 1:500-1:2000
Gel: 8%SDS-PAGE
Lysates (from left to right): HT-29 cell and human placenta tissue
Amount of lysate: 40ug per lane
Primary antibody: 1/450 dilution
Secondary antibody dilution: 1/8000
Exposure time: 30 seconds
This gene encodes a member of the deoxyribonuclease I family. The encoded protein hydrolyzes DNA, is not inhibited by actin, and mediates the breakdown of DNA during apoptosis. Mutations in this gene are a cause of systemic lupus erythematosus-16. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.?
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et al,Deficient DNASE1L3 facilitates neutrophil extracellular traps-induced invasion via cyclic GMP-AMP synthase and the non-canonical NF-jB pathway in diabetic hepatocellular carcinoma In Clin Transl Immunology on 2022 Apr 20 by Na Li, Xue Zheng, et al..PMID: 35474906
, (2022),
PMID:
35474906
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