产品详情
产品名称MAGEA10 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen affinity purification.
应用WB IHC
种属反应性Human
特异性The antibody detects endogenous levels of total MAGEA10 protein.
免疫原类型Recombinant Protein
免疫原描述Fusion protein corresponding to a region derived from internal residues of human melanoma antigen family A, 10
基因/蛋白名称MAGEA10
标记Unconjugated
别名CT1.10; MAGE10
数据库入口号Swiss-Prot#: P43363
NCBI Gene ID: 4109
Gene Accssion: BC004105/P43363
Uniprot
P43363
实际分子量41kd
浓度2.3mg/ml
配方Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
保存Store at -20˚C
应用详情
Western blotting: 1:1000-1:5000
Immunohistochemistry: 1:50-1:200
Gel: 8%SDS-PAGE
Lysate: 40ug A375 cell
Primary antibody: 1/400 dilution
Secondary antibody dilution: 1/8000
Exposure time: 20 seconds
Immunohistochemical analysis of paraffin-embedded Human esophagus cancer tissue using #36594 at dilution 1/50.
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Alternative splicing results in multiple transcript variants.?
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et al,Establishment of cancer/testis antigen profiling based on clinicopathological characteristics in resected pathological stage III non-small cell lung cancer.In Cancer Manag Res.On 2018 Jul 16 by Jin S, Cao S et al..PMID: 30038519
, (2018),
PMID:
30038519
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