产品详情
产品名称OS9 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen affinity purification.
应用WB
种属反应性Human;Mouse
特异性The antibody detects endogenous levels of total OS9 protein.
免疫原类型Recombinant Protein
免疫原描述Fusion protein corresponding to a region derived from internal residues of human osteosarcoma amplified 9, endoplasmic reticulum lectin
基因/蛋白名称OS9
标记Unconjugated
别名OS-9; ERLEC2
数据库入口号Swiss-Prot#: Q13438
NCBI Gene ID: 10956
Gene Accssion: BC007254
Uniprot
Q13438
实际分子量76kd
浓度2.4mg/ml
配方Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
保存Store at -20˚C
应用详情
Western blotting: 1:500-1:2000
Gel: 6%SDS-PAGE
Lysates (from left to right): K562 and NIH/3T3 cell
Amount of lysate: 40ug per lane
Primary antibody: 1/200 dilution
Secondary antibody dilution: 1/8000
Exposure time: 3 minutes
This gene encodes a protein that is highly expressed in osteosarcomas. This protein binds to the hypoxia-inducible factor 1 (HIF-1), a key regulator of the hypoxic response and angiogenesis, and promotes the degradation of one of its subunits. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
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et al,Peroxiredoxin 4 deficiency induces accelerated ovarian aging through destroyed proteostasis in granulosa cells. In Biochim Biophys Acta Mol Basis Dis on 2024 Oct by Xiaofei Zou, Xiuru Liang et al..PMID:38971505
, (2024),
PMID:
38971505
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