产品详情
产品名称RAC1 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen affinity purification.
应用WB
种属反应性Human;Mouse;Rat
特异性The antibody detects endogenous levels of total RAC1 protein.
免疫原类型Peptide
免疫原描述Synthetic peptide corresponding to a region derived from internal residues of human Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
基因/蛋白名称RAC1
标记Unconjugated
别名MIG5; Rac-1; TC-25; p21-Rac1
数据库入口号Swiss-Prot#: P63000
NCBI Gene ID: 5879
Gene Accssion: NP_061485
Uniprot
P63000
实际分子量23kd
浓度1mg/ml
配方Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
保存Store at -20˚C
应用详情
Western blotting: 1:200-1:1000
Gel: 12%SDS-PAGE
Lysates (from left to right): Human fetal brain tissue
Amount of lysate: 40ug per lane
Primary antibody: 1/500 dilution
Secondary antibody dilution: 1/8000
Exposure time: 1 minute
The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for this gene.
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et al,Nox4 is involved in high glucose-induced apoptosis in renal tubular epithelial cells via Notch pathway.In Mol Med Rep on 2017 Jun by Min Yao, Feng Gao,et al..PMID: 28487945
, (2017),
PMID:
28487945
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