产品详情
产品名称FGF2 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen affinity purification.
应用WB IHC
种属反应性Human;Mouse;Rat
特异性The antibody detects endogenous levels of total FGF2 protein.
免疫原类型Peptide
免疫原描述Synthetic peptide corresponding to a region derived from internal residues of human Fibroblast growth factor 2
基因/蛋白名称FGF2
标记Unconjugated
别名BFGF; FGFB; FGF-2; HBGF-2
数据库入口号Swiss-Prot#: P09038
NCBI Gene ID: 2247
Gene Accssion: NP_001997
Uniprot
P09038
实际分子量31kd
浓度2.7mg/ml
配方Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
保存Store at -20˚C
应用详情
Western blotting: 1:1000-1:5000
Immunohistochemistry: 1:100-1:500
Gel: 8%SDS-PAGE
Lysates (from left to right): Mouse lung tissue
Amount of lysate: 30ug per lane
Primary antibody: 1/1000 dilution
Secondary antibody dilution: 1/8000
Exposure time: 10 seconds
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue using #36769 at dilution 1/100.
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.
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