产品详情
产品名称CCR2 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen affinity purification.
应用WB IHC
种属反应性Human;Mouse
特异性The antibody detects endogenous levels of total CCR2 protein.
免疫原类型Peptide
免疫原描述Synthetic peptide corresponding to a region derived from internal residues of human chemokine (C-C motif) receptor 2
基因/蛋白名称CCR2
标记Unconjugated
别名CKR2; CCR-2; CCR2A; CCR2B; CD192; CKR2A; CKR2B; CMKBR2; MCP-1-R; CC-CKR-2
数据库入口号Swiss-Prot#: P41597
NCBI Gene ID: 729230
Gene Accssion: NP_001116513
Uniprot
P41597
实际分子量42kd
浓度1.7mg/ml
配方Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
保存Store at -20˚C
应用详情
Western blotting: 1:500-1:2000
Immunohistochemistry: 1:25-1:100
Gel: 8%SDS-PAGE
Lysates (from left to right): Mouse skin tissue
Amount of lysate: 40ug per lane
Primary antibody: 1/450 dilution
Secondary antibody dilution: 1/8000
Exposure time: 5 minutes
Immunohistochemical analysis of paraffin-embedded Human brain tissue using #36784 at dilution 1/20.
This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene.
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et al,Levo-Corydalmine Alleviates Neuropathic Cancer Pain Induced by Tumor Compression via the CCL2/CCR2 Pathway.In Molecules on 2017 Jun 6 by Yahui Hu, Nandani Darshika Kodithuwakku,et al..PMID: 28587280
, (2017),
PMID:
28587280
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