产品详情
产品名称ING1 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen affinity purification.
应用WB
种属反应性Human;Mouse
特异性The antibody detects endogenous levels of total ING1 protein.
免疫原类型Peptide
免疫原描述Synthetic peptide corresponding to residues near the N terminal of human inhibitor of growth family, member 1
基因/蛋白名称ING1
标记Unconjugated
别名p33; p47; p33ING1; p24ING1c; p33ING1b; p47ING1a
数据库入口号Swiss-Prot#: Q9UK53
NCBI Gene ID: 3621
Gene Accssion: NP_005528
Uniprot
Q9UK53
实际分子量47kd
浓度1.6mg/ml
配方Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
保存Store at -20˚C
应用详情
Western blotting: 1:500-1:2000
Gel: 8%SDS-PAGE
Lysates (from left to right): Hela cell and mouse brain tissue, Jurkat and Raw264.7 cell
Amount of lysate: 40ug per lane
Primary antibody: 1/267 dilution
Secondary antibody dilution: 1/8000
Exposure time: 1 second
This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.
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et al,Cytoplasmic expression of p33ING1b is correlated with tumorigenesis and progression of head and neck squamous cell carcinoma. In Histol Histopathol on 2011 May by Xiao-Han Li, Akira Noguchi, et al..PMID: 21432775
, (2011),
PMID:
21432775
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