产品详情
产品名称ABCG1 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen affinity purification.
应用WB IHC
种属反应性Human
特异性The antibody detects endogenous levels of total ABCG1 protein.
免疫原类型Peptide
免疫原描述Synthetic peptide corresponding to a region derived from internal residues of human ATP-binding cassette, sub-family G (WHITE), member 1
基因/蛋白名称ABCG1
标记Unconjugated
别名ABC8; WHITE1
数据库入口号Swiss-Prot#: P45844
NCBI Gene ID: 9619
Gene Accssion: NP_004906
Uniprot
P45844
实际分子量76kd
浓度1.2mg/ml
配方Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
保存Store at -20˚C
应用详情
Western blotting: 1:500-1:2000
Immunohistochemistry: 1:25-1:100
Gel: 10%SDS-PAGE
Lysate: 40ug HT-29 cell
Primary antibody: 1/500 dilution
Secondary antibody dilution: 1/8000
Exposure time: 2 minutes
Immunohistochemical analysis of paraffin-embedded Human gastric cancer tissue using #37074 at dilution 1/40.
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. It is involved in macrophage cholesterol and phospholipids transport, and may regulate cellular lipid homeostasis in other cell types. Six alternative splice variants have been identified.
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et al,Niacin-induced lysosomal free cholesterol efflux via LXRα-mediated signaling pathways in macrophages retards the progression of atherosclerosis
, (2025),
PMID:
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