产品详情
产品名称ITGA2 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen affinity purification.
应用WB IHC
种属反应性Human
特异性The antibody detects endogenous levels of total ITGA2 protein.
免疫原类型Peptide
免疫原描述Synthetic peptide corresponding to residues near the C terminal of human integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
基因/蛋白名称ITGA2
标记Unconjugated
别名BR; GPIa; CD49B; HPA-5; VLA-2; VLAA2
数据库入口号Swiss-Prot#: P17301
NCBI Gene ID: 3673
Gene Accssion: NP_002194
Uniprot
P17301
实际分子量129kd
浓度1.2mg/ml
配方Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
保存Store at -20˚C
应用详情
Western blotting: 1:500-1:2000
Immunohistochemistry: 1:25-1:100
Gel: 6%SDS-PAGE
Lysates (from left to right): Human lung cancer tissue and A431 cell
Amount of lysate: 40ug per lane
Primary antibody: 1/300 dilution
Secondary antibody dilution: 1/8000
Exposure time: 40 seconds
Immunohistochemical analysis of paraffin-embedded Human gastric cancer tissue using #37117 at dilution 1/15.
This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants.
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et al,Inhibition of neurogenic and thromboxane A 2 -induced human prostate smooth muscle contraction by the integrin α2β1 inhibitor BTT-3033 and the integrin-linked kinase inhibitor Cpd22. In Prostate on 2020 Aug by Bingsheng Li, Xiaolong Wang, et al..PMID:32449814
, (2020),
PMID:
32449814
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