产品详情
产品名称MAGEA3 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen affinity purification.
应用WB IHC
种属反应性Human
特异性The antibody detects endogenous levels of total MAGEA3 protein.
免疫原类型Peptide
免疫原描述Synthetic peptide corresponding to residues near the C terminal of human melanoma antigen family A, 3
基因/蛋白名称MAGEA3
标记Unconjugated
别名HIP8; HYPD; CT1.3; MAGE3; MAGEA6
数据库入口号Swiss-Prot#: P43357
NCBI Gene ID: 4102
Gene Accssion: NP_005353/P43357
Uniprot
P43357
实际分子量35kd
浓度2.9mg/ml
配方Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
保存Store at -20˚C
应用详情
Western blotting: 1:500-1:2000
Immunohistochemistry: 1:50-1:200
Gel: 10%SDS-PAGE
Lysates (from left to right): Human testis tissue, A549 and PC3 cell
Amount of lysate: 40ug per lane
Primary antibody: 1/400 dilution
Secondary antibody dilution: 1/8000
Exposure time: 2 minutes
Immunohistochemical analysis of paraffin-embedded Human tonsil tissue using #37138 at dilution 1/50.
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita.
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et al,Establishment of cancer/testis antigen profiling based on clinicopathological characteristics in resected pathological stage III non-small cell lung cancer.In Cancer Manag Res.On 2018 Jul 16 by Jin S, Cao S et al..PMID: 30038519
, (2018),
PMID:
30038519
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