产品详情
产品名称ITGA6 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen affinity purification.
应用IHC
种属反应性Human;Mouse
特异性The antibody detects endogenous levels of total ITGA6 protein.
免疫原类型Peptide
免疫原描述Synthetic peptide corresponding to a region derived from internal residues of human integrin, alpha 6
基因/蛋白名称ITGA6
标记Unconjugated
别名CD49f; VLA-6; ITGA6B
数据库入口号Swiss-Prot#: P23229
NCBI Gene ID: 3655
Gene Accssion: NP_000201
Uniprot
P23229
浓度1.7mg/ml
配方Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
保存Store at -20˚C
应用详情
Immunohistochemistry: 1:25-1:100
Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue using #37155 at dilution 1/50.
The ITGA6 protein product is the integrin alpha chain alpha 6. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Two transcript variants encoding different isoforms have been found for this gene.
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et al,Increased Expression of Integrin Alpha 6 in Nucleus Pulposus Cells in Response to High Oxygen Tension Protects against Intervertebral Disc Degeneration
, (2021),
PMID:
34707783
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