产品详情
产品名称PPARA Rabbit mAb
来源种属Rabbit
克隆性Monoclonal
纯化Protein A
应用WB
种属反应性Human;Mouse;Rat
特异性Endogenous
免疫原描述Peroxisome proliferator-activated receptor alpha
基因/蛋白名称PPARA
标记Unconjugated
别名PPARA ; NR1C1 ; PPAR ; Peroxisome proliferator-activated receptor alpha ; PPAR-alpha ; Nuclear receptor subfamily 1 group C member 1
数据库入口号Swiss-Prot#: Q07869
NCBI Gene ID: 5465
Gene Accssion: NP_005027
Uniprot
Q07869
Gene ID
5465
计算分子量52 kDa
实际分子量52 kDa
浓度1mg/ml
配方PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
保存Store at -20˚C
应用详情
WB 1:1000-1:5000
Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with PPARA antibody. The HRP-conjugated Goat anti-Rabbit IgG(H + L) antibody was used to detect the antibody. Lane 1: HepG2 Lane 2: MCF7 Lane 3: NIH-3T3 Lane 4: L6 Predicted band size: 52kDa Observed band size: 52kDa
Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined.
如果您使用该产品37219发表了文章，请通知我们，让我们可以引用您的文献。
et al,Fenofibrate suppressed proliferation and migration of human neuroblastoma cells via oxidative stress dependent of TXNIP upregulation.In Biochem Biophys Res Commun
on 2015 May 15 by Cunjin Su, Aiming Shi et al..PMID:25839662
, (2015),
PMID:
25839662
有货
