产品详情
产品名称S1PR3 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen affinity purification.
应用WB IHC
种属反应性Human
特异性The antibody detects endogenous levels of total S1PR3 protein.
免疫原类型Peptide
免疫原描述Synthetic peptide corresponding to a region derived from internal residues of human Sphingosine-1-phosphate receptor 3
基因/蛋白名称S1PR3
标记Unconjugated
别名EDG3; LPB3; S1P3; EDG-3
数据库入口号Swiss-Prot#: Q99500
NCBI Gene ID: 1903
Gene Accssion: NP_005217
Uniprot
Q99500
实际分子量42kd
浓度1.4mg/ml
配方Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
保存Store at -20˚C
应用详情
Western blotting: 1:1000-1:5000
Immunohistochemistry: 1:25-1:100
Gel: 10%SDS-PAGE
Lysates (from left to right): Human fetal brain tissue
Amount of lysate: 40ug per lane
Primary antibody: 1/700 dilution
Secondary antibody dilution: 1/8000
Exposure time: 20 seconds
Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue using #37289 at dilution 1/30.
This gene encodes a member of the EDG family of receptors, which are G protein-coupled receptors. This protein has been identified as a functional receptor for sphingosine 1-phosphate and likely contributes to the regulation of angiogenesis and vascular endothelial cell function. Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis.
如果您使用该产品37289发表了文章，请通知我们，让我们可以引用您的文献。
et al,ApoM-S1P Modulates Ox-LDL-Induced Inflammation Through the PI3K/Akt SignalIng Pathway In HUVECs. In Inflammation on 2019 Apr by Zheng Z, Zeng Y,et al.. PMID:30377890
, (2019),
PMID:
30377890
有货
