产品详情
产品名称FZD10 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen affinity purification.
应用IHC
种属反应性Human;Mouse
特异性The antibody detects endogenous levels of total FZD10 protein.
免疫原类型Peptide
免疫原描述Synthetic peptide corresponding to a region derived from internal residues of human frizzled family receptor 10
基因/蛋白名称FZD10
标记Unconjugated
别名Fz10; FzE7; CD350; FZ-10; hFz10
数据库入口号Swiss-Prot#: Q9ULW2
NCBI Gene ID: 11211
Gene Accssion: NP_009128
Uniprot
Q9ULW2
浓度1.9mg/ml
配方Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
保存Store at -20˚C
应用详情
Immunohistochemistry: 1:50-1:200
Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue using #37298 at dilution 1/50.
Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissue using #37298 at dilution 1/50.
This gene is a member of the frizzled gene family. Members of this family encode 7-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Using array analysis, expression of this intronless gene is significantly up-regulated in two cases of primary colon cancer.
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et al,METTL3 regulates m6A in endometrioid epithelial ovarian cancer independently of METTl14 and WTAP
, (2020),
PMID:
32869897
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