产品详情
产品名称HTR2C Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen affinity purification.
应用WB
种属反应性Human
特异性The antibody detects endogenous levels of total HTR2C protein.
免疫原类型Peptide
免疫原描述Synthetic peptide corresponding to residues near the C terminal of human 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
基因/蛋白名称HTR2C
标记Unconjugated
别名HTR1C; 5-HT2C; 5HTR2C; 5-HTR2C
数据库入口号Swiss-Prot#: P28335
NCBI Gene ID: 3358
Gene Accssion: NP_000859
Uniprot
P28335
实际分子量52kd
浓度2mg/ml
配方Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
保存Store at -20˚C
应用详情
Western blotting: 1:200-1:1000
Gel: 8%SDS-PAGE
Lysate: 60ug Jurkat cell
Primary antibody: 1/300 dilution
Secondary antibody dilution: 1/8000
Exposure time: 1 minute
Serotonin (5-hydroxytryptamine, 5-HT), a neurotransmitter, elicits a wide array of physiological effects by binding to several receptor subtypes, including the 5-HT2 family of seven-transmembrane-spanning, G-protein-coupled receptors, which activate phospholipase C and D signaling pathways. This gene encodes the 2C subtype of serotonin receptor and its mRNA is subject to multiple RNA editing events, where genomically encoded adenosine residues are converted to inosines.?
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et al,The epigenetic role of HTR1A antagonist in facilitating GnRH expression for pubertal initiation control
, (2021),
PMID:
34458005
et al,The epigenetic role of HTR1A antagonist in facilitating GnRH expression for pubertal initiation control
, (2021),
PMID:
34458005
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