产品详情
产品名称ATP7A Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen affinity purification.
应用WB IHC
种属反应性Human
特异性The antibody detects endogenous levels of total ATP7A protein.
免疫原类型Peptide
免疫原描述Synthetic peptide corresponding to residues near the C terminal of human ATPase, Cu++ transporting, alpha polypeptide
基因/蛋白名称ATP7A
标记Unconjugated
别名MK; MNK; DSMAX; SMAX3
数据库入口号Swiss-Prot#: Q04656
NCBI Gene ID: 538
Gene Accssion: NP_000043
Uniprot
Q04656
实际分子量163kd
浓度4mg/ml
配方Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
保存Store at -20˚C
应用详情
Western blotting: 1:200-1:1000
Immunohistochemistry: 1:50-1:200
Gel: 6%SDS-PAGE
Lysate: 40ug HepG2 cell
Primary antibody: 1/800 dilution
Secondary antibody dilution: 1/8000
Exposure time: 10 minutes
Immunohistochemical analysis of paraffin-embedded Human gastric cancer tissue using #37432 at dilution 1/50.
This gene encodes a transmembrane protein that functions in copper transport across membranes. This protein is localized to the trans Golgi network, where it is predicted to supply copper to copper-dependent enzymes in the secretory pathway. It relocalizes to the plasma membrane under conditions of elevated extracellular copper, and functions in the efflux of copper from cells. Mutations in this gene are associated with Menkes disease, X-linked distal spinal muscular atrophy, and occipital horn syndrome. Alternatively-spliced transcript variants have been observed.?
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et al,Establishment and experimental validation of a novel cuproptosis-related gene signature for prognostic implication in cholangiocarcinoma.In Front Oncol
. 2022 Dec 8 by Jialu Chen , Xiaopeng Yu , et al..PMID:36568224
, (2022),
PMID:
36568224
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