产品详情
产品名称STK3/STK4 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen affinity purification.
应用WB IHC
种属反应性Human;Mouse
特异性The antibody detects endogenous levels of total STK3/STK4 protein.
免疫原类型Peptide
免疫原描述Synthetic peptide corresponding to a region derived from internal residues of human serine threonine kinase 3/4
基因/蛋白名称STK3-STK4
标记Unconjugated
别名KRS1; MST2/KRS2; MST1; YSK3; TIIAC
数据库入口号Swiss-Prot#: Q13043
NCBI Gene ID: 6789
Gene Accssion: NP_006273
Uniprot
Q13043
实际分子量56kd
浓度3mg/ml
配方Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
保存Store at -20˚C
应用详情
Western blotting: 1:500-1:2000
Immunohistochemistry: 1:50-1:200
Gel: 6%SDS-PAGE
Lysates (from left to right): Human bladder carcinoma tissue and A172 cell, human brain malignant glioma tissue
Amount of lysate: 40ug per lane
Primary antibody: 1/1000 dilution
Secondary antibody dilution: 1/8000
Exposure time: 10 seconds
Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue using #37462 at dilution 1/70.
Sterile-20 (Ste20) is a serine/threonine kinase in Saccharomyces cerevisiae that is involved in relaying signals from G protein-coupled receptors to cyto-solic MAP kinase cascades. Mammalian protein kinases that display sequence similarity to Ste20 are divided into two groups, the PAK subfamily and the GCK subfamily.?The mammalian Ste20-like kinases (MST kinases), also known as Krs proteins, are members of the GCK subfamily. Ksr-1 (MST-2) and Ksr-2 (MST-1) are both direct substrates of caspase-3 that accelerate caspase-3 activation.
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et al,RAS-association domain family 1A regulates the abnormal cell proliferation in psoriasis via inhibition of Yes-associated protein
, (2021),
PMID:
33960627
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