产品详情
产品名称ERP29 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen affinity purification.
应用WB IHC
种属反应性Human;Mouse;Rat
特异性The antibody detects endogenous levels of total ERP29 protein.
免疫原类型Peptide
免疫原描述Synthetic peptide corresponding to a region derived from internal residues of human endoplasmic reticulum protein 29
基因/蛋白名称ERP29
标记Unconjugated
别名ERp28; ERp31; PDIA9; PDI-DB; C12orf8
数据库入口号Swiss-Prot#: P30040
NCBI Gene ID: 10961
Gene Accssion: NP_006808
Uniprot
P30040
实际分子量29kd
浓度2.6mg/ml
配方Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
保存Store at -20˚C
应用详情
Western blotting: 1:500-1:2000
Immunohistochemistry: 1:50-1:200
Gel: 10%SDS-PAGE
Lysates (from left to right): Hela cell and human fetal liver tissue, A549 and 293T cell
Amount of lysate: 40ug per lane
Primary antibody: 1/200 dilution
Secondary antibody dilution: 1/8000
Exposure time: 40 seconds
Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue using #37555 at dilution 1/40.
This gene encodes a reticuloplasmin, a protein which resides in the lumen of the endoplasmic reticulum (ER). The protein shows sequence similarity to the protein disulfide isomerase family. However, it lacks the thioredoxin motif characteristic of this family, suggesting that this protein does not function as a disulfide isomerase. The protein dimerizes and is thought to play a role in the processing of secretory proteins within the ER. Alternative splicing results in multiple transcript variants encoding different isoforms
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et al,miR-205-5p downregulation decreases gemcitabIne sensitivity of breast cancer cells via ERp29 upregulation. In Exp Ther Med on 2019 Nov by Ma C, Shi X, et al..PMID:31602229
, (2019),
PMID:
31602229