产品详情
产品名称ICAM3 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen affinity purification.
应用WB IHC
种属反应性Human
特异性The antibody detects endogenous levels of total ICAM3 protein.
免疫原类型Peptide
免疫原描述Synthetic peptide corresponding to a region derived from internal residues of human intercellular adhesion molecule 3
基因/蛋白名称ICAM3
标记Unconjugated
别名CD50; CDW50; ICAM-R
数据库入口号Swiss-Prot#: P32942
NCBI Gene ID: 3385
Gene Accssion: NP_002153/P32942
Uniprot
P32942
实际分子量60kd
浓度1.4mg/ml
配方Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
保存Store at -20˚C
应用详情
Western blotting: 1:500-1:2000
Immunohistochemistry: 1:25-1:100
Gel: 6%SDS-PAGE
Lysate: 40ug Jurkat cell
Primary antibody: 1/348 dilution
Secondary antibody dilution: 1/8000
Exposure time: 1 minute
Immunohistochemical analysis of paraffin-embedded Human gastric cancer tissue using #37638 at dilution 1/20.
The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule.
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et al,Identification of lactate metabolism-related genes for glioma metabolic reprogramming
, (2022),
PMID:
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