产品详情
产品名称KCNK9 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen affinity purification.
应用WB IHC
种属反应性Human
特异性The antibody detects endogenous levels of total KCNK9 protein.
免疫原类型Peptide
免疫原描述Synthetic peptide corresponding to a region derived from internal residues of human potassium channel, subfamily K, member 9
基因/蛋白名称KCNK9
标记Unconjugated
别名KT3.2; TASK3; K2p9.1; TASK-3
数据库入口号Swiss-Prot#: Q9NPC2
NCBI Gene ID: 51305
Gene Accssion: NP_001269463
Uniprot
Q9NPC2
实际分子量42kd
浓度2.8mg/ml
配方Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
保存Store at -20˚C
应用详情
Western blotting: 1:500-1:2000
Immunohistochemistry: 1:100-1:300
Gel: 8%SDS-PAGE
Lysates (from left to right): Human paraneoplastic and normal kidney tissue
Amount of lysate: 40ug per lane
Primary antibody: 1/650 dilution
Secondary antibody dilution: 1/8000
Exposure time: 40 seconds
Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using #37678 at dilution 1/40.
This gene encodes a protein that contains multiple transmembrane regions and two pore-forming P domains and functions as a pH-dependent potassium channel. Amplification and overexpression of this gene have been observed in several types of human carcinomas. This gene is imprinted in the brain, with preferential expression from the maternal allele. A mutation in this gene was associated with Birk-Barel mental retardation dysmorphism syndrome. Alternative splicing results in multiple transcript variants.
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et al,Potassium channels related to primary aldosteronism: Expression similarities and differences between human and rat adrenals.In Mol Cell Endocrinol on 2015 Dec 5 by Andrew X Chen , Koshiro Nishimoto et al..PMID: 26375812
, (2015),
PMID:
26375812
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