产品详情
产品名称PIK3CB Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen affinity purification.
应用IHC
种属反应性Human
特异性The antibody detects endogenous levels of total PIK3CB protein.
免疫原类型Peptide
免疫原描述Synthetic peptide corresponding to a region derived from internal residues of human phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
基因/蛋白名称PIK3CB
标记Unconjugated
别名PI3K; PIK3C1; P110BETA; PI3KBETA
数据库入口号Swiss-Prot#: P42338
NCBI Gene ID: 5291
Gene Accssion: NP_006210/P42338
Uniprot
P42338
浓度3.1mg/ml
配方Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
保存Store at -20˚C
应用详情
Immunohistochemistry: 1:50-1:200
Immunohistochemical analysis of paraffin-embedded Human brain tissue using #37828 at dilution 1/50.
Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using #37828 at dilution 1/50.
This gene encodes an isoform of the catalytic subunit of phosphoinositide 3-kinase (PI3K). These kinases are important in signaling pathways involving receptors on the outer membrane of eukaryotic cells and are named for their catalytic subunit. The encoded protein is the catalytic subunit for PI3Kbeta (PI3KB). PI3KB has been shown to be part of the activation pathway in neutrophils which have bound immune complexes at sites of injury or infection. Alternative splicing results in multiple transcript variants.?
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et al,CSF-1R regulates non-small cell lung cancer cells dissemination through Wnt3a signaling.
, (2017),
PMID:
29218239
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