产品详情
产品名称PKMYT1 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen affinity purification.
应用WB IHC
种属反应性Human;Mouse
特异性The antibody detects endogenous levels of total PKMYT1 protein.
免疫原类型Peptide
免疫原描述Synthetic peptide corresponding to a region derived from internal residues of human protein kinase, membrane associated tyrosine/threonine 1
基因/蛋白名称PKMYT1
标记Unconjugated
别名MYT1
数据库入口号Swiss-Prot#: Q99640
NCBI Gene ID: 9088
Gene Accssion: NP_004194 /Q99640
Uniprot
Q99640
实际分子量55kd
浓度3mg/ml
配方Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
保存Store at -20˚C
应用详情
Western blotting: 1:200-1:1000
Immunohistochemistry: 1:50-1:200
Gel: 8%SDS-PAGE
Lysates (from left to right): Mouse heart tissue
Amount of lysate: 40ug per lane
Primary antibody: 1/200 dilution
Secondary antibody dilution: 1/8000
Exposure time: 2 minutes
Immunohistochemical analysis of paraffin-embedded Human brain tissue using #37829 at dilution 1/50.
This gene encodes a member of the serine/threonine protein kinase family. The encoded protein is a membrane-associated kinase that negatively regulates the G2/M transition of the cell cycle by phosphorylating and inactivating cyclin-dependent kinase 1. The activity of the encoded protein is regulated by polo-like kinase 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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et al,PKMYT1 is associated with prostate cancer malignancy and may serve as a therapeutic target.In Gene on 2020 Mar 29 by Wang J, Wang L, et al..PMID:32234541
, (2020),
PMID:
32234541
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