产品详情
产品名称FASN antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB,IHC,IF
种属反应性Human;Mouse;Rat
特异性The antibody detects endogenous level of total FASN protein.
免疫原类型Recombinant Protein
免疫原描述Recombinant fusion protein of human Fatty Acid Synthase (FASN) (NP_004095.4).
基因/蛋白名称FASN
标记Unconjugated
别名FAS;OA-519;SDR27X1;FASN
数据库入口号Uniprot:P49327
GeneID:2194
Uniprot
P49327
Gene ID
2194
实际分子量273KDa
浓度1.0mg/ml
配方PBS with 0.02% sodium azide,50% glycerol,pH7.3.
保存Store at -20˚C. Avoid freeze / thaw cycles.
应用详情
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using Fatty Acid Synthase (FASN) antibody.
Immunohistochemistry of paraffin-embedded human breast cancer using Fatty Acid Synthase (FASN) antibody.
Immunofluorescence analysis of C6 cells using Fatty Acid Synthase (FASN) Rabbit pAb.
Immunofluorescence analysis of NIH/3T3 cells using Fatty Acid Synthase (FASN) Rabbit pAb.
Immunofluorescence analysis of U2OS cells using Fatty Acid Synthase (FASN) Rabbit pAb.
The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.
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et al,Hepatoprotective effects of Xiaoyao San formula on hepatic steatosis and inflammation via regulating the sex hormones metabolism. In World J Hepatol on 2024 Jul 27 by Xiao-Li Mei , Shu-Yi Wu ,et al..PMID:39086531
, (2024),
PMID:
39086531
Yes
