产品详情
产品名称ALPL antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB,IHC
种属反应性Human;Mouse;Rat
特异性The antibody detects endogenous level of total ALPL protein.
免疫原类型Recombinant Protein
免疫原描述Recombinant fusion protein of human Alkaline Phosphatase (Alkaline Phosphatase (ALPL)) (NP_000469.3).
基因/蛋白名称ALPL
标记Unconjugated
别名ALPL;AP-TNAP;APTNAP;HOPS;TNAP
数据库入口号Uniprot:P05186
GeneID:249
Uniprot
P05186
Gene ID
249
实际分子量80KDa
浓度1.0mg/ml
配方PBS with 0.02% sodium azide,50% glycerol,pH7.3.
保存Store at -20˚C. Avoid freeze / thaw cycles.
应用详情
WB 1:500 - 1:2000
IHC 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using Alkaline Phosphatase (ALPL) antibody.
Immunohistochemistry of paraffin-embedded human colon carcinoma using Alkaline Phosphatase (ALPL) Rabbit pAb.
Immunohistochemistry of paraffin-embedded human lung cancer using Alkaline Phosphatase (ALPL) Rabbit pAb.
This gene encodes a member of the alkaline phosphatase family of proteins. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This enzyme may play a role in bone mineralization. Mutations in this gene have been linked to hypophosphatasia, a disorder that is characterized by hypercalcemia and skeletal defects.
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et al,Surface mIneralized biphasic calcium phosphate ceramics loaded with urIne-derived stem cells are effective In bone regeneration. In J Orthop Surg Res on 2019 Dec 9 by XIng , Li L, et al..PMID:31818319
, (2019),
PMID:
31818319
Yes
