产品详情
产品名称COL2A1 antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB,IHC
种属反应性Human;Mouse
特异性The antibody detects endogenous level of total COL2A1 protein.
免疫原类型Recombinant Protein
免疫原描述Recombinant fusion protein of human COL2A1 (NP_149162.2).
基因/蛋白名称COL2A1
标记Unconjugated
别名COL2A1;ANFH;AOM;COL11A3;SEDC;STL1
数据库入口号Uniprot:P02458
GeneID:1280
Uniprot
P02458
Gene ID
1280
实际分子量141kDa
浓度1.0mg/ml
配方PBS with 0.02% sodium azide,50% glycerol,pH7.3.
保存Store at -20˚C. Avoid freeze / thaw cycles.
应用详情
WB 1:500 - 1:2000
IHC 1:50 - 1:200
Western blot analysis of extracts of mouse liver, using COL2A1 antibody.
Immunohistochemistry of paraffin-embedded Human breast cancer using COL2A1 Rabbit pAb.
This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene.
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et al,Blocking ACSL6 Compromises Autophagy via FLI1‐Mediated Downregulation of COLs to Radiosensitize Lung Cancer. In Adv Sci (Weinh) on 2024 Oct by Wen Ding, Shijun Bao,et al..PMID:39206814
, (2024),
PMID:
39206814
Yes
