产品详情
产品名称RAGE antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antibodies were purified by affinity purification using immunogen.
应用WB,IHC
种属反应性Human;Mouse;Rat
特异性The antibody detects endogenous level of total RAGE protein.
免疫原类型Recombinant Protein
免疫原描述Recombinant protein of human RAGE.
基因/蛋白名称RAGE
标记Unconjugated
别名MOK; RAGE; RAGE-1; RAGE1;
数据库入口号Swiss-Prot#: Q9UQ07
NCBI Gene ID: 5891
Uniprot
Q9UQ07
实际分子量48kd
浓度1.0mg/ml
配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
保存Store at -20˚C
应用详情
WB 1:500 - 1:2000
IHC 1:50 - 1:200
Western blot analysis of extracts of mouse liver, using MOK antibody at 1:1000 dilution.
Immunohistochemistry of paraffin-embedded mouse kidney using MOK antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded rat heart using MOK antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human liver using MOK antibody at dilution of 1:100 (40x lens).
This gene belongs to the MAP kinase superfamily. The gene was found to be regulated by caudal type transcription factor 2 (Cdx2) protein. The encoded protein, which is localized to epithelial cells in the intestinal crypt, may play a role in growth arrest and differentiation of cells of upper crypt and lower villus regions. Multiple alternatively spliced transcript variants encoding different isoforms have been observed for this gene. [provided by RefSeq, Dec 2012]
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et al,Silencing of advanced glycosylation and glycosylation and product-specific receptor (RAGE) inhibits the metastasis and growth of non-small cell lung cancer.In Am J Transl Res on 2017Jun 15 by Yan Xia Yu, Wen Chong Pan,et al..PMID: 28670367
, (2017),
PMID:
28670367
Yes
