产品详情
产品名称PDGFRA antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB,IHC,IF
种属反应性Human;Mouse;Rat
特异性The antibody detects endogenous level of total PDGFRA protein.
免疫原类型Recombinant Protein
免疫原描述Recombinant fusion protein of human PDGFRA (NP_006197.1).
基因/蛋白名称PDGFRA
标记Unconjugated
别名PDGFRA;CD140A;PDGFR-2;PDGFR2;GAS9;RHEPDGFRA
数据库入口号Uniprot:P16234
GeneID:5156
Uniprot
P16234
Gene ID
5156
实际分子量150-190KDa
浓度1.0mg/ml
配方PBS with 0.02% sodium azide,50% glycerol,pH7.3.
保存Store at -20˚C. Avoid freeze / thaw cycles.
应用详情
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using PDGFRA antibody.
Immunohistochemistry of paraffin-embedded mouse heart using PDGFRA Rabbit pAb.
Immunohistochemistry of paraffin-embedded rat spleen using PDGFRA Rabbit pAb.
Immunofluorescence analysis of U-2 OS cells using PDGFRA Rabbit pAb.
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.
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et al,Single-cell RNA-Seq reveals the heterogeneity of fibroblasts within the tympanojugular paraganglioma microenvironment. In Heliyon
on 2024 Jul 31 by Shengming Wang, Boya Zhang, et al..PMID:39170307
, (2024),
PMID:
39170307
Yes
