产品详情
产品名称Wnt5a antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB
种属反应性Human;Mouse;Rat
特异性The antibody detects endogenous level of total Wnt5a protein.
免疫原类型Recombinant Protein
免疫原描述Recombinant fusion protein of human WNT5A (NP_003383.2).
基因/蛋白名称Wnt5a
标记Unconjugated
别名hWNT5A;Wnt5a;WNT5A
数据库入口号Uniprot:P41221
GeneID:7474
Uniprot
P41221
Gene ID
7474
实际分子量45KDa
浓度1.0mg/ml
配方PBS with 0.02% sodium azide,50% glycerol,pH7.3.
保存Store at -20˚C. Avoid freeze / thaw cycles.
应用详情
WB 1:500 - 1:2000
Western blot analysis of extracts of various cell lines, using WNT5A antibody.
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene encodes a member of the WNT family that signals through both the canonical and non-canonical WNT pathways. This protein is a ligand for the seven transmembrane receptor frizzled-5 and the tyrosine kinase orphan receptor 2. This protein plays an essential role in regulating developmental pathways during embryogenesis. This protein may also play a role in oncogenesis. Mutations in this gene are the cause of autosomal dominant Robinow syndrome. Alternate splicing results in multiple transcript variants.
如果您使用该产品38376发表了文章，请通知我们，让我们可以引用您的文献。
et al,Yiguanjian decoction inhibits macrophage M1 polarization and attenuates hepatic fibrosis induced by CCl4/2-AAF. In Pharm Biol on 2021 Dec by Ying Xu, Wen Xu,
et al..PMID:34425061
, (2021),
PMID:
34425061
Yes
