产品详情
产品名称HMGB1 antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB,IHC
种属反应性Human;Mouse;Rat
特异性The antibody detects endogenous level of total HMGB1 protein.
免疫原类型Recombinant Protein
免疫原描述A synthetic peptide of human HMGB1 (NP_002119.1).
基因/蛋白名称HMGB1
标记Unconjugated
别名HMG-1;HMG1;HMG3;SBP-1;HMGB1
数据库入口号Uniprot:P09429
GeneID:3146
Uniprot
P09429
Gene ID
3146
实际分子量29KDa
浓度1.0mg/ml
配方PBS with 0.02% sodium azide,50% glycerol,pH7.3.
保存Store at -20˚C. Avoid freeze / thaw cycles.
应用详情
WB 1:500 - 1:2000
IHC 1:50 - 1:200
Western blot analysis of extracts of MCF7 cells, using [KO Validated] HMGB1 Rabbit pAb.
Immunohistochemistry of paraffin-embedded rat brain using HMGB1 Antibody.
Immunohistochemistry of paraffin-embedded human breast cancer using HMGB1 Antibody.
Immunohistochemistry of paraffin-embedded mouse heart using HMGB1 Antibody.
This gene encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants that encode the same protein.
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et al,Oleandrin, a cardiac glycoside, induces immunogenic cell death via the PERK/elF2伪/ATF4/CHOP pathway in breast cancer. In Cell Death Dis on 2021 Mar 24 by
Xiaoxi Li, Jian Zheng, et al..PMID:33762577
, (2021),
PMID:
33762577
et al,Biodegradable iridium coordinated nanodrugs potentiate photodynamic therapy and immunotherapy of lung cancer.
, (2025),
PMID:
39488900
货期一周
