产品详情
产品名称CX3CR1 antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB,IHC,IF
种属反应性Human;Mouse;Rat
特异性The antibody detects endogenous level of total CX3CR1 protein.
免疫原类型Peptide
免疫原描述A synthetic peptide of human CX3CR1
基因/蛋白名称CX3CR1
标记Unconjugated
别名CX3CR1;CCRL1;CMKBRL1;CMKDR1;GPR13;GPRV28;V28
数据库入口号Uniprot:P49238
GeneID:1524
Uniprot
P49238
Gene ID
1524
实际分子量52KDa
浓度1.0mg/ml
配方PBS with 0.02% sodium azide,50% glycerol,pH7.3.
保存Store at -20˚C. Avoid freeze / thaw cycles.
应用详情
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using CX3CR1 antibody.
Immunohistochemistry of paraffin-embedded human colon carcinoma using CX3CR1 Rabbit pAb.
Immunohistochemistry of paraffin-embedded rat spleen using CX3CR1 Rabbit pAb.
Immunofluorescence analysis of THP-1 cells using CX3CR1 Rabbit pAb.
Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Four transcript variants encoding two different isoforms have been found for this gene.
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et al,Dysregulated expression of miR-140 and miR122 compromised microglial chemotaxisand led to reduced restriction of ADpathology
, (2024),
PMID:
et al,Dysregulated expression of miR-140 and miR-122 compromised microglial chemotaxis and led to reduced restriction of AD pathology
, (2024),
PMID:
Yes
