产品详情
产品名称IL2RA antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB,IHC,IF
种属反应性Human;Mouse;Rat
特异性The antibody detects endogenous level of total IL2RA protein.
免疫原类型Peptide
免疫原描述A synthetic peptide of human IL2RA
基因/蛋白名称IL2RA
标记Unconjugated
别名IL2RA;CD25;IDDM10;IL2R;IMD41;TCGFR;p55
数据库入口号Uniprot:P01589
GeneID:3559
Uniprot
P01589
Gene ID
3559
实际分子量60KDa
浓度1.0mg/ml
配方PBS with 0.02% sodium azide,50% glycerol,pH7.3.
保存Store at -20˚C. Avoid freeze / thaw cycles.
应用详情
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using IL2RA antibody.
Immunohistochemistry of paraffin-embedded human tonsil using IL2RA Rabbit pAb.
Immunohistochemistry of paraffin-embedded rat spleen using IL2RA Rabbit pAb.
Immunofluorescence analysis of rat spleen cells using IL2RA Rabbit pAb.
The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.
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et al,CD155 Cooperates with PD-1/PD-L1 to Promote Proliferation of Esophageal Squamous Cancer Cells via PI3K/Akt and MAPK Signaling Pathways. In Cancers (Basel) on 2022 Nov 15 by Xiyang Tan, Jie Yang, et al..PMID:36428703
, (2022),
PMID:
36428703
Yes
