产品详情
产品名称MMP11 antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antibodies were purified by affinity purification using immunogen.
应用WB
种属反应性Human;Mouse;Rat
特异性The antibody detects endogenous level of total MMP11 protein.
免疫原类型Peptide
免疫原描述A synthetic peptide of human MMP11.
基因/蛋白名称MMP11
标记Unconjugated
别名ST3; SL-3; STMY3
数据库入口号Swiss-Prot#: P24347
NCBI Gene ID: 4320
Uniprot
P24347
实际分子量55kd
浓度1.0mg/ml
配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
保存Store at -20˚C
应用详情
Western blotting: 1:500 - 1:2000
Immunohistochemistry: 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using MMP11 antibody at 1:500 dilution.
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix.
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et al,miR-125a-3p suppresses the growth and progression of papillary thyroid carcInoma cell by targetIng MMP11. In J Cell Biochem on 2019 Sep 6. by Song M, Wang N, et al..PMID:31489990
, (2019),
PMID:
31489990
et al,miR-125a-3p suppresses the growth and progression of papillary thyroid carcinoma cell by targeting MMP11.In J Cell Biochem on 2020 Feb; by Song M, Wang N, et al..PMID:31489990
, (2020),
PMID:
31489990
Yes
