产品详情
产品名称G3BP1 antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antibodies were purified by affinity purification using immunogen.
应用WB,IHC,IF
种属反应性Human;Mouse;Rat
特异性The antibody detects endogenous level of total G3BP1 protein.
免疫原类型Recombinant Protein
免疫原描述Recombinant protein of human G3BP1.
基因/蛋白名称G3BP1
标记Unconjugated
别名G3BP; HDH-VIII;
数据库入口号Swiss-Prot#: Q13283
NCBI Gene ID: 10146
Uniprot
Q13283
实际分子量52kd
浓度1.0mg/ml
配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
保存Store at -20˚C
应用详情
Western blotting: 1:500 - 1:2000
Immunofluorescence: 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using G3BP1 antibody at 1:1000 dilution.
Immunohistochemistry of paraffin-embedded rat liver using G3BP1 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded rat spleen using G3BP1 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human liver cancer using G3BP1 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse spleen using G3BP1 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse heart using G3BP1 antibody at dilution of 1:100 (40x lens).
This gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
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et al,Pyruvate Kinase M (PKM) binds ribosomes in a poly-ADP ribosylation dependent manner to induce translational stalling In Nucleic Acids Res On2023 Jul 7byNevraj S Kejiou , Lena Ilan et al..PMID:37224531
, (2023),
PMID:
37224531
Yes
