产品详情
产品名称MLKL antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antibodies were purified by affinity purification using immunogen.
应用WB,IHC,IF
种属反应性Human;Mouse
特异性The antibody detects endogenous level of total MLKL protein.
免疫原类型Recombinant Protein
免疫原描述Recombinant protein of human MLKL.
基因/蛋白名称MLKL
标记Unconjugated
别名9130019I15Rik;
数据库入口号Swiss-Prot#: Q8NB16
NCBI Gene ID: 74568
Uniprot
Q8NB16
实际分子量54kd
浓度1.0mg/ml
配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
保存Store at -20˚C
应用详情
Western blotting: 1:500 - 1:2000
Western blot analysis of extracts of various cell lines, using MLKL antibody at 1:1000 dilution.
Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.
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Yes
