免费电话:400-9961-933
邮箱:info@sabbiotech.com
欢迎光临本站
川博智能体 English
位置: 首页 > 多克隆抗体 > DMP1 antibody

DMP1 antibody#38779

是否有货: Yes
产品详情

产品名称DMP1 antibody

来源种属Rabbit

克隆性Polyclonal

亚型IgG

纯化Affinity purification

应用WB,IHC

种属反应性Human;Mouse;Rat

特异性The antibody detects endogenous level of DMP1 protein.

免疫原类型Recombinant Protein

免疫原描述Recombinant fusion protein of human DMP1 (NP_004398.1).

基因/蛋白名称DMP1

标记Unconjugated

别名DMP1;ARHP;ARHR;DMP-1

数据库入口号Uniprot:Q13316
GeneID:1758

Uniprot Q13316

Gene ID 1758

计算分子量"Predicted band size: 54; 55 kD; Observed band size: 102 kD"

实际分子量56kd

浓度1.0mg/ml

配方"Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide. "

保存Store at -20˚C. Avoid freeze / thaw cycles.

应用详情

WB 1/500 - 1/1000
IHC 1:50-1:100

Western blot analysis of DMP1 expression in U251 (A), mouse brain (B), rat brain (C) whole cell lysates.
Immunohistochemical analysis of DMP1 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. Tyramide-AF488 (green) was used as the chromogen. The section was then counterstained with DAPI (blue).

Dentin matrix acidic phosphoprotein is an extracellular matrix protein and a member of the small integrin binding ligand N-linked glycoprotein family. This protein, which is critical for proper mineralization of bone and dentin, is present in diverse cells of bone and tooth tissues. The protein contains a large number of acidic domains, multiple phosphorylation sites, a functional arg-gly-asp cell attachment sequence, and a DNA binding domain. In undifferentiated osteoblasts it is primarily a nuclear protein that regulates the expression of osteoblast-specific genes. During osteoblast maturation the protein becomes phosphorylated and is exported to the extracellular matrix, where it orchestrates mineralized matrix formation. Mutations in the gene are known to cause autosomal recessive hypophosphatemia, a disease that manifests as rickets and osteomalacia. The gene structure is conserved in mammals. Two transcript variants encoding different isoforms have been described for this gene.

如果您使用该产品38779发表了文章,请通知我们,让我们可以引用您的文献。

et al,KPNB1-ATF4 induces BNIP3-dependent mitophagy to drive odontoblastic differentiation in dental pulp stem cells. In Cell Mol Biol Lett on 2024 Nov 27 by Zeying Zhang, Di Yang,et al..PMID:39604846 , (2024),
PMID: 39604846

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk
;

联系我们

Location :

南京市高新开发区星火路10号人才大厦C座

Phone :

400-9961-933
025-58868422

Email Address

info@sabbiotech.com