产品详情
产品名称PHC3 antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB
种属反应性Human;Mouse;Rat
特异性The antibody detects endogenous level of total PHC3 protein.
免疫原类型Recombinant Protein
免疫原描述Recombinant fusion protein of human PHC3 (NP_079223.3).
基因/蛋白名称PHC3
标记Unconjugated
别名PHC3;EDR3;HPH3
数据库入口号Uniprot:Q8NDX5
GeneID:80012
Uniprot
Q8NDX5
Gene ID
80012
实际分子量106kDa
浓度1.0mg/ml
配方PBS with 0.02% sodium azide,50% glycerol,pH7.3.
保存Store at -20˚C. Avoid freeze / thaw cycles.
应用详情
WB 1:500 - 1:2000
Western blot analysis of extracts of various cell lines, using PHC3 Antibody.
Component of a Polycomb group (PcG multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
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