产品详情
产品名称PANX1 antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antibodies were purified by affinity purification using immunogen.
应用WB IF
种属反应性Human
特异性The antibody detects endogenous level of total PANX1 protein.
免疫原类型Recombinant Protein
免疫原描述Recombinant protein of human PANX1.
基因/蛋白名称PANX1
标记Unconjugated
别名PX1; MRS1; UNQ2529;
数据库入口号Swiss-Prot#: Q96RD7
NCBI Gene ID: 24145
Uniprot
Q96RD7
实际分子量48kd
浓度1.0mg/ml
配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
保存Store at -20˚C
应用详情
Western blotting: 1:500 - 1:2000
Immunofluorescence: 1:50 - 1:100
Immunofluorescence analysis of U2OS cell using PANX1 antibody. Blue: DAPI for nuclear staining.
The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 2 are abundantly expressed in central nerve system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 2 may form cell type-specific gap junctions with distinct properties.
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et al,Platelet pannexin-1 channels modulate inflammation during abdominal aortic aneurysm formation.
, (2022),
PMID:
et al,Platelet pannexin-1 channels modulate neutrophil activation and migration but not the progression of abdominal aortic aneurysmInFront Mol BiosciOn2023 Mar 6byLisa Maria Metz?1,?Tobias Feige? et al..PMID:?36950521
, (2023),
PMID:
36950521
et al,The role of the platelet pannexin 1 channel in thrombosis, hemostasis and the development of abdominal aortic aneurysmsInOnby et al..PMID:
, (2023),
PMID:
Yes
