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位置: 首页 > 多克隆抗体 > CD63 Antibody

CD63 Antibody#40192

是否有货: 货期1周
产品详情

产品名称CD63 Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antigen affinity purification.

应用ELISA, WB, IHC

种属反应性Human;Mouse;Rat

特异性The antibody detects endogenous levels of total CD63 protein.

免疫原类型Peptide

免疫原描述Synthetic peptide of human CD63 molecule

基因/蛋白名称CD63

标记Unconjugated

别名MLA1; ME491; LAMP-3; OMA81H; TSPAN30

数据库入口号Swiss-Prot:P08962
Gene Accssion:NP_001244318

Uniprot P08962

实际分子量26KD

浓度0.8mg/ml

配方Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

保存Store at -20˚C

应用详情

WB :500-2000 

IHC :50-200

Gel: 12%SDS-PAGE Lysate: 40 ug Lane 1-4: LNCAP, NIH/3T3, THP-1, Mouse small intestines tissue lysates Primary antibody: at dilution 1/800 Secondary antibody: at 1/5000 dilution Exposure time: 30 seconds
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: 200)
The image on the left is immunohistochemistry of paraffin-embedded Human bladder cancer tissue at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: 200)

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms.

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et al,Exosomes Derived from Akt -Modified Human Umbilical Cord Mesenchymal Stem Cells Improve Cardiac Regeneration and Promote Angiogenesis via Activating Platelet-Derived Growth Factor D. In Stem Cells Transl Med on 2017 Jan by Jie Ma, Yuanyuan Zhao, et al..PMID:28170176 , (2017),
PMID: 28170176

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk
;

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