产品详情
产品名称MAGEB2 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen affinity purification.
应用IHC
种属反应性Human
特异性The antibody detects endogenous levels of total MAGEB2 protein.
免疫原类型Peptide
免疫原描述Synthetic peptide corresponding to residues near the N terminal of human melanoma antigen family B, 2
基因/蛋白名称MAGEB2
标记Unconjugated
别名DAM6; CT3.2; MAGE-XP-2
数据库入口号Swiss-Prot:O15479
Gene Accssion:NP_002355
Uniprot
O15479
浓度2.5mg/ml
配方Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
保存Store at -20˚C
应用详情
Immunohistochemistry:1:25-1:100
Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using #40202 at dilution 1/40.
Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissue using #40202 at dilution 1/40.
This gene is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. This gene is localized in the DSS (dosage-sensitive sex reversal) critical region. It is expressed in testis and placenta, and in a significant fraction of tumors of various histological types. The MAGEB genes are clustered on chromosome Xp22-p21.?
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et al,Establishment of cancer/testis antigen profiling based on clinicopathological characteristics in resected pathological stage III non-small cell lung cancer.In Cancer Manag Res.On 2018 Jul 16 by Jin S, Cao S et al..PMID: 30038519
, (2018),
PMID:
30038519
Yes
