产品详情
产品名称CFAP45 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen affinity purification.
应用IHC
种属反应性Human
特异性The antibody detects endogenous levels of total CFAP45 protein.
免疫原类型Peptide
免疫原描述Synthetic peptide corresponding to residues near the N terminal of human cilia and flagella associated protein 45
基因/蛋白名称CFAP45
标记Unconjugated
别名NESG1; CCDC19
数据库入口号Swiss-Prot:Q9UL16
Gene Accssion:NP_036469
Uniprot
Q9UL16
浓度1.5mg/ml
配方Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
保存Store at -20˚C
应用详情
Immunohistochemistry:1:25-1:100
Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using #40364 at dilution 1/25.
CCDC19 is a 466 amino acid protein encoded by a gene mapping to human chromosome 1. Chromosome 1 is the largest human chromosome, spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1 and, considering the great number of genes, there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes Lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinson¡¯s, Gaucher disease and Usher syndrome are also associated with chromosome 1.
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et al,E3 ubiquitin ligase Smurf1 promotes cardiomyocyte pyroptosis by mediating ubiquitin-dependent degradation of TRIB2 in a rat model of heart failure
, (2025),
PMID:
39749701
Yes
