产品详情
产品名称IL6 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen affinity purification.
应用IHC
种属反应性Human
特异性The antibody detects endogenous levels of total IL6 protein.
免疫原类型protein
免疫原描述Full length fusion protein of human IL6
基因/蛋白名称IL6
标记Unconjugated
别名HGF; HSF; BSF2; IL-6; IFNB2
数据库入口号Swiss-Prot#: P05231
Gene ID: 3569
Uniprot
P05231
浓度0.2mg/ml
配方Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
保存Store at -20˚C
应用详情
Immunohistochemistry: 1:25-1:100
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue using #42709 at dilution 1/20.
Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using #42709 at dilution 1/20.
This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis.?
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et al,The role of FTO in m6A RNA methylation and immune regulation in Staphylococcus aureus infection-related osteomyelitis.
, (2025),
PMID:
39980685
Yes
