产品详情
产品名称LTA4H Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen affinity purification.
应用WB
种属反应性Human;Mouse
特异性The antibody detects endogenous levels of total LTA4H protein.
免疫原类型protein
免疫原描述Fusion protein of human LTA4H
基因/蛋白名称LTA4H
标记Unconjugated
别名Leukotriene A-4 hydrolase; leukotriene A4 hydrolase; LKHA4; LTA-4 hydrolase; LTA4; LTA4H
数据库入口号Swiss-Prot#: P09960
Gene ID: 4048
Uniprot
P09960
计算分子量69kd
浓度1mg/ml
配方Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
保存Store at -20˚C
应用详情
Western blotting: 1:500-1:2000
Immunohistochemistry: 1:10-1:50
Gel: 8%SDS-PAGE
Lysate: 40 μg
Lane: TM4 cells
Primary antibody: 1/300 dilution
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution
Exposure time: 20 seconds
LTA4H (Leukotriene A4-hydrolase ) is a Zn2+-containing enzyme with both epoxide hydrolase and aminopeptidase activity. As an epoxide hydrolase, LTA4H catalyzes the hydration of LTA4 to leukotriene B4 (LTB4, 5S,12R-dihydroxy-6,14-cis-8,10-trans-eicosatetraenoic acid), a potent lipid chemoattractant that influences inflammation, immune responses, and host defense against infection. As an aminopeptidase, LTA4H catalyzes the cleavage of amides of para-nitroaniline. The human LTA4H gene encodes a 610 amino acid protein.
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, (2020),
PMID:
32308544
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