产品详情
产品名称SWAP70 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen affinity purification.
应用IHC
种属反应性Human
特异性The antibody detects endogenous levels of total SWAP70 protein.
免疫原类型protein
免疫原描述Fusion protein of human SWAP70
基因/蛋白名称SWAP70
标记Unconjugated
别名HSPC321; SWAP-70
数据库入口号Swiss-Prot#: Q9UH65
Gene ID: 23075
Uniprot
Q9UH65
浓度1mg/ml
配方Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
保存Store at -20˚C
应用详情
Immunohistochemistry: 1:25-1:100
Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissue using #42812 at dilution 1/20.
Immunohistochemical analysis of paraffin-embedded Human tonsil tissue using #42812 at dilution 1/20.
Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion (By similarity).
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et al,Proteomic characteristics reveal the signatures and the risks of T1 colorectal cancer metastasis to lymph nodes
, (2023),
PMID:
37158593