产品详情
产品名称KCTD16 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen affinity purification.
应用WB IHC
种属反应性Human;Mouse
特异性The antibody detects endogenous levels of total KCTD16 protein.
免疫原类型protein
免疫原描述Fusion protein of human KCTD16
基因/蛋白名称KCTD16
标记Unconjugated
别名BTB/POZ domain-containing protein KCTD16; DKFZp781A1155; KCD16; KCTD16; KIAA1317; MGC138167
数据库入口号Swiss-Prot#: Q68DU8
Gene ID: 57528
Uniprot
Q68DU8
计算分子量49kd
浓度1.6mg/ml
配方Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
保存Store at -20˚C
应用详情
Western blotting: 1:500-1:2000
Immunohistochemistry: 1:25-1:100
Gel: 8%SDS-PAGE
Lysate: 40 μg
Lane: Mouse brain tissue
Primary antibody: 1/400 dilution
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution
Exposure time: 3 seconds
Immunohistochemical analysis of paraffin-embedded Human colorectal cancer tissue using #42919 at dilution 1/30.
Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using #42919 at dilution 1/30.
The BTB (Broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. KCTD16 (potassium channel tetramerisation domain containing 16), also known as BTB/POZ domain-containing protein KCTD16, is a 428 amino acid protein that contains one BTB (POZ) domain. An auxiliary subunit of GABAB R1 and GABAB R2, KCTD16 increases agonist potency and alters the G-protein signaling of the receptors by accelerating onset and promoting desensitization.
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et al,Identification and study of mood-related biomarkers and potential molecular mechanisms in type 2 diabetes mellitus.
, (2025),
PMID:
39915429
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