产品详情
产品名称SYNPO2 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen affinity purification.
应用IHC
种属反应性Human
特异性The antibody detects endogenous levels of total SYNPO2 protein.
免疫原类型peptide
免疫原描述Synthetic peptide of human SYNPO2
基因/蛋白名称SYNPO2
标记Unconjugated
别名SYNPO2
数据库入口号Swiss-Prot#: Q9UMS6
Gene ID: 171024
Uniprot
Q9UMS6
浓度2.5mg/ml
配方Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
保存Store at -20˚C
应用详情
Immunohistochemistry: 1:10-1:50
Immunohistochemical analysis of paraffin-embedded Human esophagus cancer tissue using #43152 at dilution 1/45,
Synaptopodin-2?is a?protein?that in humans is encoded by the?SYNPO2?gene. Has an actin-binding and actin-bundling activity. Synaptopodin is a proline-rich, actin-associated protein expressed in mature dendritic spines and renal podocytes. Synaptopodin appears to play a role in the actin-based plasticity of spines by linking actin to the spine apparatus.
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et al,Synaptopodin-2 promotes hepatocellular carcinoma metastasis via calcineurin-induced nuclear-cytoplasmic translocation.In Cancer Lett on 2020 Jul 10 by Gao J, Zhang HP, et al..PMID: 32278815
, (2020),
PMID:
32278815