产品详情
产品名称UGT1A6 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen affinity purification.
应用IHC
种属反应性Human
特异性The antibody detects endogenous levels of total UGT1A6 protein.
免疫原类型peptide
免疫原描述Synthetic peptide of human UGT1A6
基因/蛋白名称UGT1A6
标记Unconjugated
别名GNT1; UGT1; HLUGP; UDPGT; UGT1F; HLUGP1; UGT1A6S; UDPGT 1-6
数据库入口号Swiss-Prot#: P19224
Gene ID: 54578
Uniprot
P19224
浓度1.4mg/ml
配方Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
保存Store at -20˚C
应用详情
Immunohistochemistry: 1:100-1:200
Immunohistochemical analysis of paraffin-embedded Human Colorectal cancer tissue using #43176 at dilution 1/200.
Immunohistochemical analysis of paraffin-embedded Human Esophagus cancer tissue using #43176 at dilution 1/200.
This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene is active on phenolic and planar compounds. Alternative splicing in the unique 5' end of this gene results in two transcript variants.?
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et al,SOX1 promotes differentiation of nasopharyngeal carcinoma cells by activating retinoid metabolic pathway.In Cell Death Dis on 2020 May 7 by Lei XX, Liu Y,et al..PMID:32382038
, (2020),
PMID:
32382038
Yes
