产品详情
产品名称PRDX4 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen affinity purification.
应用WB IHC
种属反应性Human;Mouse;Rat
特异性The antibody detects endogenous levels of total PRDX4 protein.
免疫原类型peptide
免疫原描述Synthetic peptide of human PRDX4
基因/蛋白名称PRDX4
标记Unconjugated
别名PRX-4; AOE372; AOE37-2; HEL-S-97n
数据库入口号Swiss-Prot#: Q13162
Gene ID: 10549
Uniprot
Q13162
计算分子量30kd
浓度1.2mg/ml
配方Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
保存Store at -20˚C
应用详情
Western blotting: 1:500-1:2000
Immunohistochemistry: 1:25-1:100
Gel: 8%SDS-PAGE
Lysate: 40 μg
Lane 1-6: Hela,Raji,293T,HepG2,K562 and MCF-7 cell
Primary antibody: 1/300 dilution
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution
Exposure time: 2 seconds
Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue using #43303 at dilution 1/20,
The protein encoded by this gene is an antioxidant enzyme and belongs to the peroxiredoxin family. The protein is localized to the cytoplasm. Peroxidases of the peroxiredoxin family reduce hydrogen peroxide and alkyl hydroperoxides to water and alcohol with the use of reducing equivalents derived from thiol-containing donor molecules. This protein has been found to play a regulatory role in the activation of the transcription factor NF-kappaB.?
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et al,The effect of exposure time and concentration of airborne PM2.5 on lung Injury In mice: A transcriptome analysis. In Redox Biol on 2019 Sep by Wang H, Shen X et al..PMID:31279222
, (2019),
PMID:
31279222
Yes
