产品详情
产品名称PIK3CA Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen affinity purification
应用IHC
种属反应性Human
特异性The antibody detects endogenous levels of total PIK3CA protein.
免疫原类型peptide
免疫原描述Synthetic peptide of human PIK3CA
基因/蛋白名称PIK3CA
标记Unconjugated
别名MCM; CWS5; MCAP; PI3K; CLOVE; MCMTC; p110-alpha
数据库入口号Swiss-Prot#: P42336
NCBI Gene ID: 5290
Uniprot
P42336
浓度0.7mg/ml
配方Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
保存Store at -20˚C
应用详情
Immunohistochemistry: 1: 20-100
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PIK3CA Antibody at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200)
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PIK3CA Antibody at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200)
Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers.
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et al,CSF-1R regulates non-small cell lung cancer cells dissemination through Wnt3a signaling.
, (2017),
PMID:
29218239
Yes
