产品详情
产品名称VRK2 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen affinity purification
应用IHC WB
种属反应性Human
特异性The antibody detects endogenous levels of total VRK2 protein.
免疫原类型peptide
免疫原描述Synthetic peptide of human VRK2
基因/蛋白名称VRK2
标记Unconjugated
数据库入口号Swiss-Prot#: Q86Y07
NCBI Gene ID: 7444
Uniprot
Q86Y07
计算分子量58kd
浓度1.2mg/ml
配方Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
保存Store at -20˚C
应用详情
Western blotting: 1:500-2000
Immunohistochemistry: 1: 100-200
Gel: 8%SDS-PAGE
Lysate: 40 μg, Lane: Human fetal liver tissue lysate,
Primary antibody:VRK2 antibody at dilution 1/500,
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,
Exposure time: 2 seconds
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using VRK2 Antibody at dilution 1/100, on the right is treated with synthetic peptide. (Original magnification: x200)
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using VRK2 Antibody at dilution 1/100, on the right is treated with synthetic peptide. (Original magnification: x200)
This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. The encoded protein acts as an effector of signaling pathways that regulate apoptosis and tumor cell growth. Variants in this gene have been associated with schizophrenia. Alternative splicing results in multiple transcript variants that differ in their subcellular localization and biological activity.
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et al,Proteomic characteristics reveal the signatures and the risks of T1 colorectal cancer metastasis to lymph nodes
, (2023),
PMID:
37158593