产品详情
产品名称CCR4 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen affinity purification
应用IHC
种属反应性Human
特异性The antibody detects endogenous levels of total CCR4 protein.
免疫原类型peptide
免疫原描述Synthetic peptide of human CCR4
基因/蛋白名称CCR4
标记Unconjugated
别名CKR4; K5-5; CD194; CMKBR4; ChemR13; CC-CKR-4; HGCN:14099
数据库入口号Swiss-Prot#: P51679
NCBI Gene ID: 1233
Uniprot
P51679
浓度0.7mg/ml
配方Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
保存Store at -20˚C
应用详情
Immunohistochemistry: 1: 20-100
The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using CCR4 Antibody at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200)
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CCR4 Antibody at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200)
The protein encoded by this gene belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis.
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et al,SLC35A2 expression drives breast cancer progression via ERK pathway activation
, (2023),
PMID:
Yes
